Top-end all-inclusive luxury hotels in South America are a fantastic way to make the most of every moment in this spectacular continent. The number of upscale properties has grown dramatically and today you are spoilt for choice. That’s why we are here, to steer you towards the right luxury hotel for you in South America.

We have personally visited all of the luxury hotels in South America that we recommend. Therefore we provide you with honest, unbiased hotel reviews. We have a personal approach, taking the time to get to know you before we tell you which places will make your vacation experience special. We can also advise on whether it’s worth it to upgrade for a better room or view.

1. Luxury hotel : Cavas Wine Lodge, Argentina

Cavas wine lodge argentina

Set deep in Argentina’s Mendoza region, famed the world over for its wine, the Cavas Wine Lodge sits against a stunning backdrop of the Andes mountains.  As a luxury hotel it’s impeccably stylish without being snooty; every guest room and individual bungalow has its own terrace, plunge pool and open fire.


Their all-inclusive stays cover both the lodge restaurant and four others within the area, giving you exceptional freedom and variety.  The spa includes some specially crafted ‘Wine Therapy’ as well as more traditional treatments.

2. Luxury hotel : Awasi Atacama, Chile

Small pool area surrounded by sunbeds, terracotta-coloured walls and a thatched lodge at the end.

Lounge area at Awasi (click for more images)

In the heart of the Atacama desert is one of the most exquisite luxury hotels in South America that you’ll ever come across. Awasi, meaning ‘home’ in Quechua, is intimate and indulgent with 8 wood-built, thatched cabanas that feature private patios on top of the hotel’s comfortable social areas.

Guests have excellent access to the stark beauty of the Atacama with a private 4×4 car and personal guide entirely at their disposal.

3. Luxury hotel: Lapostolle Residence, Chile

Two deck chairs at the edge of a deep blue infinity pool looking out across vineyards and mountains

Lounge area at Lapostolle (click for more images)

Exclusive and serene, the Lapostolle Residence is owned by the family who produce Grand-Marnier liquor and is at the heart of Chile’s wine industry. In fact it’s a renowned winery itself.  This is one of our favourite luxury hotels in South America because it is small and intimate. You’ll stay in one of just four casitas (separate villas) looking out into the Apalta vineyards. They are decorated in contemporary taste with Chilean wood features, smooth leather and airy silks.

The menu is inspired by the wines and makes the most of local produce and seasonality – it’s an exquisite, memorable experience.

4. Luxury hotel : Titilaka, Peru

Two wooden chairs on a balcony looking out to a wide, serene lake

Balcony at Titilaka (click for more images)

If you’re heading to Lake Titicaca then this is where you should stay. We would argue that this luxury hotel has some of the best views in South America. Titilaka offers spectacular, uninterrupted vista’s across the lake which are highly instagrammable! All of their 18 bedrooms have beautiful views as do the lounge balconies that run around the exterior of the lodge.

The Titilaka hotel is attuned to the region and prides itself on the wonderful experiences it offers for guests to explore the terrain. Seasoned guides can take you hiking, boating, biking and riding through the Andean hills. They can also take you on memorable trips to visit the local, traditional communities.


5. Luxury hotel : Explora Patagonia, Chile

Looking across a rich turquoise lake, against the backdrop of high mountains, a hotel sits at the foothills on the shore.

Explora Patagonia from Lake Pehoe (click for more images)

This is undoubtedly the best place to stay in the Torres del Paine National Park and is perfectly situated for excursions into it.  The views across Lake Pehoe and the surrounding peaks are sublime – you won’t forget these in a hurry! And the lodge itself is built using beautiful graduated woods and has every amenity you’d expect from a luxury hotel – gourmet cuisine, a bathhouse and spa with sumptuous rooms.

Explora Patagonia is also the only hotel lodge in the region with its own stables with specially-trained horses and expert handlers.


Contact Latin Odyssey to find out about staying in any of the above lodges.

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